October 12, 2015
Short Tandem Repeat (STR) Markers Coding and Billing Guidelines (CM00034)
Effective for dates of service on and after January 1, 2014.
©CPT code 81265 describes services performed for recipient/donor testing and twin zygosity. Although recipient/donor testing is appropriate for the Medicare population, twin zygosity testing would not be expected in the Medicare population. Laboratories are encouraged to register tests based on the use of the test. Through the MolDX identification process, Palmetto would pay a claim submitted with CPT code 81265 and an ID for a registered recipient/donor test. Tests registered for twin zygosity testing would be denied as a statutorily excluded service. CPT code 81266 for each additional specimen applies to twin zygosity testing and will be auto-denied as a statutory exclusion.

